Tag: TMP-SMX and warfarin
Trimethoprim-Sulfamethoxazole and Warfarin: What You Need to Know About INR Elevation
Posted by Ellison Greystone on Dec, 7 2025
Trimethoprim-sulfamethoxazole can cause dangerous INR spikes in people taking warfarin, increasing bleeding risk. Learn how this interaction works, who's most at risk, and what to do if you need an antibiotic.